Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Serine/threonine-protein kinase pim-1' and Ligand = 'BDBM50174140'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Serine/threonine-protein kinase pim-1 (Homo sapiens (Human))	BDBM50174140 (CHEMBL3809940) Show SMILES [H][C@]12CNC(=O)c3cc([nH]c13)-c1cccc3nc(C)c(NC\C(C)=C/C2)nc13 |r,c:25| Show InChI InChI=1S/C21H21N5O/c1-11-6-7-13-10-23-21(27)15-8-17(25-18(13)15)14-4-3-5-16-19(14)26-20(22-9-11)12(2)24-16/h3-6,8,13,25H,7,9-10H2,1-2H3,(H,22,26)(H,23,27)/b11-6-/t13-/m0/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	0.400	n/a	n/a	n/a	n/a	n/a	n/a
Amgen Inc. Curated by ChEMBL					Assay Description Inhibition of human full-length Pim1 expressed in Escherichia coli assessed as phosphorylation of biotinylated BAD peptide at Ser-112 preincubated fo...				ACS Med Chem Lett 7: 408-12 (2016) Article DOI: 10.1021/acsmedchemlett.5b00403 BindingDB Entry DOI: 10.7270/Q2MG7RD5
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