Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Serine/threonine-protein kinase pim-1' and Ligand = 'BDBM50383272'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Serine/threonine-protein kinase pim-1 (Homo sapiens (Human))	BDBM50383272 (CHEMBL2032375) Show SMILES N[C@H]1CC[C@@H](CC1)Nc1cncc(n1)-c1cccc(C=C2SC(O)=NC2=O)c1 |r,w:19.20,wU:4.7,wD:1.0,c:25,(23.62,-22.34,;23.63,-20.8,;24.96,-20.02,;24.96,-18.48,;23.62,-17.72,;22.29,-18.49,;22.29,-20.02,;23.62,-16.18,;22.28,-15.42,;20.95,-16.2,;19.61,-15.42,;19.61,-13.89,;20.95,-13.12,;22.28,-13.88,;20.95,-11.58,;19.61,-10.81,;19.61,-9.27,;20.94,-8.5,;22.28,-9.26,;23.61,-8.48,;24.94,-9.25,;24.92,-10.78,;26.38,-11.28,;26.84,-12.75,;27.3,-10.05,;26.42,-8.79,;26.91,-7.33,;22.28,-10.81,)| Show InChI InChI=1S/C20H21N5O2S/c21-14-4-6-15(7-5-14)23-18-11-22-10-16(24-18)13-3-1-2-12(8-13)9-17-19(26)25-20(27)28-17/h1-3,8-11,14-15H,4-7,21H2,(H,23,24)(H,25,26,27)/t14-,15-	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	0.470	n/a	n/a	n/a	n/a	n/a	n/a
Genzyme Corp. Curated by ChEMBL					Assay Description Inhibition of human Pim-1 using 5-FAM-RSRHSSYPAGT-CONH2 as substrate preincubated for 15 mins prior substrate addition measured after 45 mins by fluo...				J Med Chem 55: 2641-8 (2012) Article DOI: 10.1021/jm2014698 BindingDB Entry DOI: 10.7270/Q2Q2418B
					More data for this Ligand-Target Pair