Compile Data Set for Download or QSAR

Found 2 hits Enz. Inhib. hit(s) with Target = 'Serine/threonine-protein kinase pim-1' and Ligand = 'BDBM50510165'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Serine/threonine-protein kinase pim-1 (Homo sapiens (Human))	BDBM50510165 (CHEMBL4543342) Show SMILES CN1CCC(CNc2cccc3ccc(nc23)-c2nnc3c4OCCN(C)c4cnn23)CC1 Show InChI InChI=1S/C24H28N8O/c1-30-10-8-16(9-11-30)14-25-18-5-3-4-17-6-7-19(27-21(17)18)23-28-29-24-22-20(15-26-32(23)24)31(2)12-13-33-22/h3-7,15-16,25H,8-14H2,1-2H3	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	14	n/a	n/a	n/a	n/a	n/a	n/a
Spanish National Cancer Research Centre (CNIO) Curated by ChEMBL					Assay Description Inhibition of His tagged human recombinant PIM1 using PIM tide (ARKRRRHPSGPPTA) as substrate incubated for 1 hr by fluorescence based assay				Eur J Med Chem 168: 87-109 (2019) Article DOI: 10.1016/j.ejmech.2019.02.022 BindingDB Entry DOI: 10.7270/Q2XW4P4J
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase pim-1 (Homo sapiens (Human))	BDBM50510165 (CHEMBL4543342) Show SMILES CN1CCC(CNc2cccc3ccc(nc23)-c2nnc3c4OCCN(C)c4cnn23)CC1 Show InChI InChI=1S/C24H28N8O/c1-30-10-8-16(9-11-30)14-25-18-5-3-4-17-6-7-19(27-21(17)18)23-28-29-24-22-20(15-26-32(23)24)31(2)12-13-33-22/h3-7,15-16,25H,8-14H2,1-2H3	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	179	n/a	n/a	n/a	n/a
Spanish National Cancer Research Centre (CNIO) Curated by ChEMBL					Assay Description Inhibition of PIM1 in human NCI-H1299 cells assessed as reduction in BAD phosphorylation at Ser-112 residue incubated for 4 hrs by ELISA				Eur J Med Chem 168: 87-109 (2019) Article DOI: 10.1016/j.ejmech.2019.02.022 BindingDB Entry DOI: 10.7270/Q2XW4P4J
					More data for this Ligand-Target Pair