Compile Data Set for Download or QSAR

Found 2 hits Enz. Inhib. hit(s) with Target = 'Serine/threonine-protein kinase pim-1' and Ligand = 'BDBM50510170'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Serine/threonine-protein kinase pim-1 (Homo sapiens (Human))	BDBM50510170 (CHEMBL4468395) Show SMILES CN1CCC(CC1)Nc1cccc2ccc(nc12)-c1nnc2c3OCCN(C)c3cnn12 Show InChI InChI=1S/C23H26N8O/c1-29-10-8-16(9-11-29)25-17-5-3-4-15-6-7-18(26-20(15)17)22-27-28-23-21-19(14-24-31(22)23)30(2)12-13-32-21/h3-7,14,16,25H,8-13H2,1-2H3	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	7	n/a	n/a	n/a	n/a	n/a	n/a
Spanish National Cancer Research Centre (CNIO) Curated by ChEMBL					Assay Description Inhibition of His tagged human recombinant PIM1 using PIM tide (ARKRRRHPSGPPTA) as substrate incubated for 1 hr by fluorescence based assay				Eur J Med Chem 168: 87-109 (2019) Article DOI: 10.1016/j.ejmech.2019.02.022 BindingDB Entry DOI: 10.7270/Q2XW4P4J
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase pim-1 (Homo sapiens (Human))	BDBM50510170 (CHEMBL4468395) Show SMILES CN1CCC(CC1)Nc1cccc2ccc(nc12)-c1nnc2c3OCCN(C)c3cnn12 Show InChI InChI=1S/C23H26N8O/c1-29-10-8-16(9-11-29)25-17-5-3-4-15-6-7-18(26-20(15)17)22-27-28-23-21-19(14-24-31(22)23)30(2)12-13-32-21/h3-7,14,16,25H,8-13H2,1-2H3	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	212	n/a	n/a	n/a	n/a
Spanish National Cancer Research Centre (CNIO) Curated by ChEMBL					Assay Description Inhibition of PIM1 in human NCI-H1299 cells assessed as reduction in BAD phosphorylation at Ser-112 residue incubated for 4 hrs by ELISA				Eur J Med Chem 168: 87-109 (2019) Article DOI: 10.1016/j.ejmech.2019.02.022 BindingDB Entry DOI: 10.7270/Q2XW4P4J
					More data for this Ligand-Target Pair