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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Serine/threonine-protein kinase pim-2' and Ligand = 'BDBM161991'   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Serine/threonine-protein kinase pim-2


(Homo sapiens (Human))		BDBM161991
PNG
(US9682991, 40)
Show SMILES CC1CN(C)c2c(NCC3CCN(C)CC3)nn3c(nnc3c2O1)-c1cccc(OC(F)(F)F)c1
Show InChI InChI=1S/C23H28F3N7O2/c1-14-13-32(3)18-19(34-14)22-29-28-21(16-5-4-6-17(11-16)35-23(24,25)26)33(22)30-20(18)27-12-15-7-9-31(2)10-8-15/h4-6,11,14-15H,7-10,12-13H2,1-3H3,(H,27,30)
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
antibodypedia
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PC cid
PC sid
UniChem
US Patent
n/an/a 550n/an/an/an/an/an/a



FUNDACIÓN CENTRO NACIONAL DE INVESTIGACIONES ONCOLOGICAS CARLOS III

US Patent


Assay Description
The biochemical assay to measure PIM-2 activity relies on the ADP Hunter assay kit (DiscoveRx Corp., Cat. #90-0077), that determines the amount of AD...

US Patent US9682991 (2017)


BindingDB Entry DOI: 10.7270/Q2513WCB
More data for this
Ligand-Target Pair