Compile Data Set for Download or QSAR

Found 4 hits Enz. Inhib. hit(s) with Target = 'Serine/threonine-protein kinase pim-2' and Ligand = 'BDBM238510'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Serine/threonine-protein kinase pim-2 (Homo sapiens (Human))	BDBM238510 (US9394297, 140 | US9394297, 141) Show SMILES Cc1nc2cccc(-c3cc4c(CCNC4=O)[nH]3)c2nc1N[C@@H]1CCC[C@H](N)C1 Show InChI InChI=1S/C22H26N6O/c1-12-21(26-14-5-2-4-13(23)10-14)28-20-15(6-3-7-18(20)25-12)19-11-16-17(27-19)8-9-24-22(16)29/h3,6-7,11,13-14,27H,2,4-5,8-10,23H2,1H3,(H,24,29)(H,26,28)/t13-,14+/m0/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<0.100	n/a	n/a	n/a	n/a	7.0	22
AMGEN INC. US Patent					Assay Description The assay for the determination of Pim activity is based on the formation of phosphorylated biotinylated-BAD peptide at the Serine 112 residue (S112)...				US Patent US9394297 (2016) BindingDB Entry DOI: 10.7270/Q2G44P78
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase pim-2 (Homo sapiens (Human))	BDBM238510 (US9394297, 140 | US9394297, 141) Show SMILES Cc1nc2cccc(-c3cc4c(CCNC4=O)[nH]3)c2nc1N[C@@H]1CCC[C@H](N)C1 Show InChI InChI=1S/C22H26N6O/c1-12-21(26-14-5-2-4-13(23)10-14)28-20-15(6-3-7-18(20)25-12)19-11-16-17(27-19)8-9-24-22(16)29/h3,6-7,11,13-14,27H,2,4-5,8-10,23H2,1H3,(H,24,29)(H,26,28)/t13-,14+/m0/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.200	n/a	n/a	n/a	n/a	7.0	22
AMGEN INC. US Patent					Assay Description The assay for the determination of Pim activity is based on the formation of phosphorylated biotinylated-BAD peptide at the Serine 112 residue (S112)...				US Patent US9394297 (2016) BindingDB Entry DOI: 10.7270/Q2G44P78
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase pim-2 (Homo sapiens (Human))	BDBM238510 (US9394297, 140 | US9394297, 141) Show SMILES Cc1nc2cccc(-c3cc4c(CCNC4=O)[nH]3)c2nc1N[C@@H]1CCC[C@H](N)C1 Show InChI InChI=1S/C22H26N6O/c1-12-21(26-14-5-2-4-13(23)10-14)28-20-15(6-3-7-18(20)25-12)19-11-16-17(27-19)8-9-24-22(16)29/h3,6-7,11,13-14,27H,2,4-5,8-10,23H2,1H3,(H,24,29)(H,26,28)/t13-,14+/m0/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	3.5	n/a	n/a	n/a	n/a	7.0	22
AMGEN INC. US Patent					Assay Description The assay for the determination of Pim activity is based on the formation of phosphorylated biotinylated-BAD peptide at the Serine 112 residue (S112)...				US Patent US9394297 (2016) BindingDB Entry DOI: 10.7270/Q2G44P78
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase pim-2 (Homo sapiens (Human))	BDBM238510 (US9394297, 140 | US9394297, 141) Show SMILES Cc1nc2cccc(-c3cc4c(CCNC4=O)[nH]3)c2nc1N[C@@H]1CCC[C@H](N)C1 Show InChI InChI=1S/C22H26N6O/c1-12-21(26-14-5-2-4-13(23)10-14)28-20-15(6-3-7-18(20)25-12)19-11-16-17(27-19)8-9-24-22(16)29/h3,6-7,11,13-14,27H,2,4-5,8-10,23H2,1H3,(H,24,29)(H,26,28)/t13-,14+/m0/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	9.30	n/a	n/a	n/a	n/a	7.0	22
AMGEN INC. US Patent					Assay Description The assay for the determination of Pim activity is based on the formation of phosphorylated biotinylated-BAD peptide at the Serine 112 residue (S112)...				US Patent US9394297 (2016) BindingDB Entry DOI: 10.7270/Q2G44P78
					More data for this Ligand-Target Pair