Compile Data Set for Download or QSAR

Found 2 hits Enz. Inhib. hit(s) with Target = 'Serine/threonine-protein kinase pim-2' and Ligand = 'BDBM238539'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Serine/threonine-protein kinase pim-2 (Homo sapiens (Human))	BDBM238539 (US9394297, 183) Show SMILES Cc1nc2cccc(-c3cc4c(CCNC4=O)[nH]3)c2nc1Nc1ccccc1 Show InChI InChI=1S/C22H19N5O/c1-13-21(25-14-6-3-2-4-7-14)27-20-15(8-5-9-18(20)24-13)19-12-16-17(26-19)10-11-23-22(16)28/h2-9,12,26H,10-11H2,1H3,(H,23,28)(H,25,27)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	1.60	n/a	n/a	n/a	n/a	7.0	22
AMGEN INC. US Patent					Assay Description The assay for the determination of Pim activity is based on the formation of phosphorylated biotinylated-BAD peptide at the Serine 112 residue (S112)...				US Patent US9394297 (2016) BindingDB Entry DOI: 10.7270/Q2G44P78
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase pim-2 (Homo sapiens (Human))	BDBM238539 (US9394297, 183) Show SMILES Cc1nc2cccc(-c3cc4c(CCNC4=O)[nH]3)c2nc1Nc1ccccc1 Show InChI InChI=1S/C22H19N5O/c1-13-21(25-14-6-3-2-4-7-14)27-20-15(8-5-9-18(20)24-13)19-12-16-17(26-19)10-11-23-22(16)28/h2-9,12,26H,10-11H2,1H3,(H,23,28)(H,25,27)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	2	n/a	n/a	n/a	n/a	n/a	n/a
Amgen Inc. Curated by ChEMBL					Assay Description Inhibition of human full-length Pim2 expressed in Escherichia coli assessed as phosphorylation of biotinylated BAD peptide at Ser 112 preincubated fo...				ACS Med Chem Lett 7: 408-12 (2016) Article DOI: 10.1021/acsmedchemlett.5b00403 BindingDB Entry DOI: 10.7270/Q2MG7RD5
					More data for this Ligand-Target Pair