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Found 1 hit Enz. Inhib. hit(s) with Target = 'Serine/threonine-protein kinase pim-2' and Ligand = 'BDBM50500180'   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Serine/threonine-protein kinase pim-2


(Homo sapiens (Human))		BDBM50500180
PNG
(CHEMBL3676284)
Show SMILES C[C@@H]1C[C@H](N)CN(C1)c1ccncc1NC(=O)c1csc(n1)-c1c(F)cccc1F
Show InChI InChI=1S/C21H21F2N5OS/c1-12-7-13(24)10-28(9-12)18-5-6-25-8-16(18)26-20(29)17-11-30-21(27-17)19-14(22)3-2-4-15(19)23/h2-6,8,11-13H,7,9-10,24H2,1H3,(H,26,29)/t12-,13+/m1/s1
PDB
MMDB

KEGG

UniProtKB/SwissProt

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PC cid
PC sid
UniChem
Article
PubMed
<3n/an/an/an/an/an/an/an/a



Novartis Institutes for Biomedical Research

Curated by ChEMBL


Assay Description
Inhibition of PIM2 kinase (unknown origin) using NH2-AGAGRSRHSSYPAGT-OH as substrate by kinase-Glo assay

J Med Chem 58: 8373-86 (2015)


Article DOI: 10.1021/acs.jmedchem.5b01275
BindingDB Entry DOI: 10.7270/Q2H41VGN
More data for this
Ligand-Target Pair