Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Serine/threonine-protein kinase pim-3' and Ligand = 'BDBM224972'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Serine/threonine-protein kinase pim-3 (Homo sapiens (Human))	BDBM224972 (US9321756, 239) Show SMILES CNc1nnc(s1)-c1ccc2[nH]cc(-c3cccc(F)n3)c2c1 Show InChI InChI=1S/C16H12FN5S/c1-18-16-22-21-15(23-16)9-5-6-12-10(7-9)11(8-19-12)13-3-2-4-14(17)20-13/h2-8,19H,1H3,(H,18,22)	KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	170	n/a	n/a	n/a	n/a	n/a	n/a
AMGEN INC. US Patent					Assay Description The assay for the determination of Pim activity is based on the formation of phosphorylated biotinylated-BAD peptide at the Serine 112 residue (S112)...				US Patent US9321756 (2016) BindingDB Entry DOI: 10.7270/Q2W094S2
					More data for this Ligand-Target Pair