Compile Data Set for Download or QSAR

Found 2 hits Enz. Inhib. hit(s) with Target = 'Serine/threonine-protein kinase pim-3' and Ligand = 'BDBM291201'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Serine/threonine-protein kinase pim-3 (Homo sapiens (Human))	BDBM291201 (N-{4-[(3S,5R)-3-Amino-5-methylpiperidin-1-yl]pyrid...) Show SMILES C[C@@H]1C[C@H](N)CN(C1)c1ccncc1NC(=O)c1ccc2ccc(cc2n1)N1CCC(CC1)c1ccncc1 |r| Show InChI InChI=1S/C31H35N7O/c1-21-16-25(32)20-38(19-21)30-8-13-34-18-29(30)36-31(39)27-5-3-24-2-4-26(17-28(24)35-27)37-14-9-23(10-15-37)22-6-11-33-12-7-22/h2-8,11-13,17-18,21,23,25H,9-10,14-16,19-20,32H2,1H3,(H,36,39)/t21-,25+/m1/s1	KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<10	n/a	n/a	n/a	n/a	n/a	n/a
Bryn Mawr College					Assay Description Pim-1 and Pim-3 kinase assays-20 uL reactions were run in white 384 well polystyrene plates dotted with 0.8 uL compound/DMSO in the assay buffer (50 ...				J Med Chem 51: 4968-77 (2008) BindingDB Entry DOI: 10.7270/Q2ZC856W
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase pim-3 (Homo sapiens (Human))	BDBM291201 (N-{4-[(3S,5R)-3-Amino-5-methylpiperidin-1-yl]pyrid...) Show SMILES C[C@@H]1C[C@H](N)CN(C1)c1ccncc1NC(=O)c1ccc2ccc(cc2n1)N1CCC(CC1)c1ccncc1 |r| Show InChI InChI=1S/C31H35N7O/c1-21-16-25(32)20-38(19-21)30-8-13-34-18-29(30)36-31(39)27-5-3-24-2-4-26(17-28(24)35-27)37-14-9-23(10-15-37)22-6-11-33-12-7-22/h2-8,11-13,17-18,21,23,25H,9-10,14-16,19-20,32H2,1H3,(H,36,39)/t21-,25+/m1/s1	KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<10	n/a	n/a	n/a	n/a	7.5	25
Incyte Corporation US Patent					Assay Description Pim-1 and Pim-3 kinase assays-20 μL reactions were run in white 384 well polystyrene plates dotted with 0.8 μL compound/DMSO in the assay b...				US Patent US9580418 (2017) BindingDB Entry DOI: 10.7270/Q2X92DB9
					More data for this Ligand-Target Pair