Compile Data Set for Download or QSAR

Found 2 hits Enz. Inhib. hit(s) with Target = 'Serine/threonine-protein kinase pim-3' and Ligand = 'BDBM291207'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Serine/threonine-protein kinase pim-3 (Homo sapiens (Human))	BDBM291207 (N-{4-[(3S,5R)-3-Amino-5-methylpiperidin-1-yl]pyrid...) Show SMILES C[C@@H]1C[C@H](N)CN(C1)c1ccncc1NC(=O)c1ccc2ccc(cc2n1)N1CCC(CC1)N1CCOCC1 |r| Show InChI InChI=1S/C30H39N7O2/c1-21-16-23(31)20-37(19-21)29-6-9-32-18-28(29)34-30(38)26-5-3-22-2-4-25(17-27(22)33-26)35-10-7-24(8-11-35)36-12-14-39-15-13-36/h2-6,9,17-18,21,23-24H,7-8,10-16,19-20,31H2,1H3,(H,34,38)/t21-,23+/m1/s1	KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<10	n/a	n/a	n/a	n/a	n/a	n/a
Bryn Mawr College					Assay Description Pim-1 and Pim-3 kinase assays-20 uL reactions were run in white 384 well polystyrene plates dotted with 0.8 uL compound/DMSO in the assay buffer (50 ...				J Med Chem 51: 4968-77 (2008) BindingDB Entry DOI: 10.7270/Q2ZC856W
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase pim-3 (Homo sapiens (Human))	BDBM291207 (N-{4-[(3S,5R)-3-Amino-5-methylpiperidin-1-yl]pyrid...) Show SMILES C[C@@H]1C[C@H](N)CN(C1)c1ccncc1NC(=O)c1ccc2ccc(cc2n1)N1CCC(CC1)N1CCOCC1 |r| Show InChI InChI=1S/C30H39N7O2/c1-21-16-23(31)20-37(19-21)29-6-9-32-18-28(29)34-30(38)26-5-3-22-2-4-25(17-27(22)33-26)35-10-7-24(8-11-35)36-12-14-39-15-13-36/h2-6,9,17-18,21,23-24H,7-8,10-16,19-20,31H2,1H3,(H,34,38)/t21-,23+/m1/s1	KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<10	n/a	n/a	n/a	n/a	7.5	25
Incyte Corporation US Patent					Assay Description Pim-1 and Pim-3 kinase assays-20 μL reactions were run in white 384 well polystyrene plates dotted with 0.8 μL compound/DMSO in the assay b...				US Patent US9580418 (2017) BindingDB Entry DOI: 10.7270/Q2X92DB9
					More data for this Ligand-Target Pair