Compile Data Set for Download or QSAR

Found 2 hits Enz. Inhib. hit(s) with Target = 'Serine/threonine-protein kinase pim-3' and Ligand = 'BDBM291210'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Serine/threonine-protein kinase pim-3 (Homo sapiens (Human))	BDBM291210 (N-{4-[(3R,4R,5S)-3-Amino-4-hydroxy-5-methylpiperid...) Show SMILES C[C@H]1CN(C[C@@H](N)[C@@H]1O)c1ccncc1NC(=O)c1ccc2ccc(cc2n1)N1CCCC1 |r| Show InChI InChI=1S/C25H30N6O2/c1-16-14-31(15-19(26)24(16)32)23-8-9-27-13-22(23)29-25(33)20-7-5-17-4-6-18(12-21(17)28-20)30-10-2-3-11-30/h4-9,12-13,16,19,24,32H,2-3,10-11,14-15,26H2,1H3,(H,29,33)/t16-,19+,24+/m0/s1	KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<10	n/a	n/a	n/a	n/a	n/a	n/a
Bryn Mawr College					Assay Description Pim-1 and Pim-3 kinase assays-20 uL reactions were run in white 384 well polystyrene plates dotted with 0.8 uL compound/DMSO in the assay buffer (50 ...				J Med Chem 51: 4968-77 (2008) BindingDB Entry DOI: 10.7270/Q2ZC856W
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase pim-3 (Homo sapiens (Human))	BDBM291210 (N-{4-[(3R,4R,5S)-3-Amino-4-hydroxy-5-methylpiperid...) Show SMILES C[C@H]1CN(C[C@@H](N)[C@@H]1O)c1ccncc1NC(=O)c1ccc2ccc(cc2n1)N1CCCC1 |r| Show InChI InChI=1S/C25H30N6O2/c1-16-14-31(15-19(26)24(16)32)23-8-9-27-13-22(23)29-25(33)20-7-5-17-4-6-18(12-21(17)28-20)30-10-2-3-11-30/h4-9,12-13,16,19,24,32H,2-3,10-11,14-15,26H2,1H3,(H,29,33)/t16-,19+,24+/m0/s1	KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<10	n/a	n/a	n/a	n/a	7.5	25
Incyte Corporation US Patent					Assay Description Pim-1 and Pim-3 kinase assays-20 μL reactions were run in white 384 well polystyrene plates dotted with 0.8 μL compound/DMSO in the assay b...				US Patent US9580418 (2017) BindingDB Entry DOI: 10.7270/Q2X92DB9
					More data for this Ligand-Target Pair