Compile Data Set for Download or QSAR

Found 2 hits Enz. Inhib. hit(s) with Target = 'Serine/threonine-protein kinase pim-3' and Ligand = 'BDBM291232'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Serine/threonine-protein kinase pim-3 (Homo sapiens (Human))	BDBM291232 (US9580418, Example 52 | US9890162, Example 52) Show SMILES C[C@H]1CN(C[C@@H](N)[C@@H]1O)c1ccncc1NC(=O)c1ccc2ccc(cc2n1)-c1ccc(OC2CCOCC2)nc1 |r| Show InChI InChI=1S/C31H34N6O4/c1-19-17-37(18-24(32)30(19)38)28-8-11-33-16-27(28)36-31(39)25-6-4-20-2-3-21(14-26(20)35-25)22-5-7-29(34-15-22)41-23-9-12-40-13-10-23/h2-8,11,14-16,19,23-24,30,38H,9-10,12-13,17-18,32H2,1H3,(H,36,39)/t19-,24+,30+/m0/s1	KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<10	n/a	n/a	n/a	n/a	n/a	n/a
Bryn Mawr College					Assay Description Pim-1 and Pim-3 kinase assays-20 uL reactions were run in white 384 well polystyrene plates dotted with 0.8 uL compound/DMSO in the assay buffer (50 ...				J Med Chem 51: 4968-77 (2008) BindingDB Entry DOI: 10.7270/Q2ZC856W
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase pim-3 (Homo sapiens (Human))	BDBM291232 (US9580418, Example 52 | US9890162, Example 52) Show SMILES C[C@H]1CN(C[C@@H](N)[C@@H]1O)c1ccncc1NC(=O)c1ccc2ccc(cc2n1)-c1ccc(OC2CCOCC2)nc1 |r| Show InChI InChI=1S/C31H34N6O4/c1-19-17-37(18-24(32)30(19)38)28-8-11-33-16-27(28)36-31(39)25-6-4-20-2-3-21(14-26(20)35-25)22-5-7-29(34-15-22)41-23-9-12-40-13-10-23/h2-8,11,14-16,19,23-24,30,38H,9-10,12-13,17-18,32H2,1H3,(H,36,39)/t19-,24+,30+/m0/s1	KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<10	n/a	n/a	n/a	n/a	7.5	25
Incyte Corporation US Patent					Assay Description Pim-1 and Pim-3 kinase assays-20 μL reactions were run in white 384 well polystyrene plates dotted with 0.8 μL compound/DMSO in the assay b...				US Patent US9580418 (2017) BindingDB Entry DOI: 10.7270/Q2X92DB9
					More data for this Ligand-Target Pair