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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Serine hydroxymethyltransferase, mitochondrial [30-504]' and Ligand = 'BDBM512956'   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Serine hydroxymethyltransferase, mitochondrial [30-504]


(Homo sapiens (Human))		BDBM512956
PNG
(US11091451, Compound I-22)
Show SMILES CC(C)(NC(=O)Cc1csc(n1)-c1cc(Cl)c(O)cc1-c1ccccc1)C(O)=O
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a<1.00E+3n/an/an/an/an/an/a


TBA

Assay Description
Full length human cytosolic Serine Hydroxymethyl transferase 1 (SHMT1, residues 1-483 in Uniport ID P34896) was expressed as an N-terminal His6 tagge...

Citation and Details

BindingDB Entry DOI: 10.7270/Q20Z76DS
More data for this
Ligand-Target Pair