Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Serine hydroxymethyltransferase, mitochondrial [30-504]' and Ligand = 'BDBM512986'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Serine hydroxymethyltransferase, mitochondrial [30-504] (Homo sapiens (Human))	BDBM512986 (US11091451, Compound I-42) Show SMILES S.OC(=O)[C@H](Cc1ccccc1)NC(=O)Cc1csc(n1)-c1ccc(Cl)cc1Cl |r| Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	2.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Full length human cytosolic Serine Hydroxymethyl transferase 1 (SHMT1, residues 1-483 in Uniport ID P34896) was expressed as an N-terminal His6 tagge...				Citation and Details BindingDB Entry DOI: 10.7270/Q20Z76DS
					More data for this Ligand-Target Pair