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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Serine palmitoyltransferase 2' and Ligand = 'BDBM50461640'   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Serine palmitoyltransferase 2


(Homo sapiens (Human))		BDBM50461640
PNG
(CHEMBL4226045)
Show SMILES COc1ccc(cc1OC)C(=O)N1CCC(Nc2ccc(Cl)cc2)c2ccc(Cl)cc12
Show InChI InChI=1S/C24H22Cl2N2O3/c1-30-22-10-3-15(13-23(22)31-2)24(29)28-12-11-20(19-9-6-17(26)14-21(19)28)27-18-7-4-16(25)5-8-18/h3-10,13-14,20,27H,11-12H2,1-2H3
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Takeda Pharmaceutical Company Limited

Curated by ChEMBL


Assay Description
Inhibition of human SPT2 transfected in Freestyle293 cells using L-serine and palmitoyl-CoA as substrate preincubated for 60 mins followed by substra...

Bioorg Med Chem 26: 2452-2465 (2018)


Article DOI: 10.1016/j.bmc.2018.04.008
BindingDB Entry DOI: 10.7270/Q2RF5XNH
More data for this
Ligand-Target Pair