BindingDB logo
myBDB logout
Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Serine protease 1' and Ligand = 'BDBM14318'   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Serine protease 1


(Bos taurus (bovine))		BDBM14318
PNG
(CRA29 | N-[(2S)-4-(azetidin-3-yl)-1-(5-{[4-(2,3-di...)
Show SMILES Fc1ccc(cc1F)C(=O)N[C@@H](CCC1CNC1)C(=O)c1noc(Cc2ccc(cc2)C(=O)NC2Cc3ccccc3C2)n1 |r|
Show InChI InChI=1S/C33H31F2N5O4/c34-26-11-10-24(16-27(26)35)33(43)38-28(12-7-20-17-36-18-20)30(41)31-39-29(44-40-31)13-19-5-8-21(9-6-19)32(42)37-25-14-22-3-1-2-4-23(22)15-25/h1-6,8-11,16,20,25,28,36H,7,12-15,17-18H2,(H,37,42)(H,38,43)/t28-/m0/s1
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Similars
Article
PubMed
 1.50E+5n/an/an/an/an/an/an/an/a



Celera



Assay Description
Each enzyme was assayed with a set of different concentrations of each inhibitor. After addition of the appropriate substrate, the rate of hydrolysis...

Biochemistry 45: 5964-73 (2006)


Article DOI: 10.1021/bi060173m
BindingDB Entry DOI: 10.7270/Q2W09450
More data for this
Ligand-Target Pair