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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Serine protease 1' and Ligand = 'BDBM50081086'   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Serine protease 1


(Homo sapiens (Human))		BDBM50081086
PNG
(CHEMBL314576 | N-((S)-1-Carbamimidoyl-2-hydroxy-pi...)
Show SMILES NC(=N)N1CCC[C@H](NC(=O)CN2c3ccccc3CC[C@H](NS(=O)(=O)Cc3ccccc3)C2=O)C1O
Show InChI InChI=1S/C25H32N6O5S/c26-25(27)30-14-6-10-19(23(30)33)28-22(32)15-31-21-11-5-4-9-18(21)12-13-20(24(31)34)29-37(35,36)16-17-7-2-1-3-8-17/h1-5,7-9,11,19-20,23,29,33H,6,10,12-16H2,(H3,26,27)(H,28,32)/t19-,20-,23?/m0/s1
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PubMed
n/an/a 26n/an/an/an/an/an/a



Corvas International, Inc.

Curated by ChEMBL


Assay Description
In vitro inhibitory activity of the compound against human enzyme trypsin

Bioorg Med Chem Lett 9: 2573-8 (1999)


BindingDB Entry DOI: 10.7270/Q26M361R
More data for this
Ligand-Target Pair