Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Serine protease HTRA3 [111-436]' and Ligand = 'BDBM521757'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Serine protease HTRA3 [111-436] (Human)	BDBM521757 (US11149067, Compound Ahp17) Show SMILES CC(C)C[C@@H]1N2[C@H](O)CC[C@H](NC(=O)[C@H](CC=C)NC(=O)[C@@H](NC(=O)[C@H](C)NC(=O)C(C)NC(=O)OCc3ccccc3)[C@@H](C)OC(=O)[C@@H](NC(=O)[C@H](Cc3ccccc3)N(C)C1=O)C(C)C)C2=O |r| Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	840	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description In general, proteolytic activity was tested by monitoring the cleavage of the specific chromogenic substrate at 405 nm wavelength for 60 or 120 minut...				Citation and Details BindingDB Entry DOI: 10.7270/Q2RR22D0
					More data for this Ligand-Target Pair