Compile Data Set for Download or QSAR

Found 2 hits Enz. Inhib. hit(s) with Target = 'Signal transducer and activator of transcription 3' and Ligand = 'BDBM50396172'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Signal transducer and activator of transcription 3 (Homo sapiens (Human))	BDBM50396172 (CHEMBL2172008) Show SMILES CCN1C(=S)S\C(=C/c2ccc(o2)-c2ccc(cc2)C(O)=O)C1=O Show InChI InChI=1S/C17H13NO4S2/c1-2-18-15(19)14(24-17(18)23)9-12-7-8-13(22-12)10-3-5-11(6-4-10)16(20)21/h3-9H,2H2,1H3,(H,20,21)/b14-9-	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.80E+4	n/a	n/a	n/a	n/a	n/a	n/a
University of Southern California Curated by ChEMBL					Assay Description Inhibition of IL6-mediated STAT3 phosphorylation in human HepG2 cells preincubated for 1 hr prior to IL6 challenge measured after 30 mins by immunobl...				J Med Chem 55: 6645-68 (2012) Article DOI: 10.1021/jm300207s BindingDB Entry DOI: 10.7270/Q2CJ8FKK
					More data for this Ligand-Target Pair
Signal transducer and activator of transcription 3 (Homo sapiens (Human))	BDBM50396172 (CHEMBL2172008) Show SMILES CCN1C(=S)S\C(=C/c2ccc(o2)-c2ccc(cc2)C(O)=O)C1=O Show InChI InChI=1S/C17H13NO4S2/c1-2-18-15(19)14(24-17(18)23)9-12-7-8-13(22-12)10-3-5-11(6-4-10)16(20)21/h3-9H,2H2,1H3,(H,20,21)/b14-9-	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	3.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
University of Southern California Curated by ChEMBL					Assay Description Inhibition of recombinant STAT3 assessed as inhibition of STAT3-phosphododecapeptide interaction by SPR analysis				J Med Chem 55: 6645-68 (2012) Article DOI: 10.1021/jm300207s BindingDB Entry DOI: 10.7270/Q2CJ8FKK
					More data for this Ligand-Target Pair