BindingDB PrimarySearch

Found 5 hits Enz. Inhib. hit(s) with Target = 'Signal transducer and activator of transcription 3' and Ligand = 'BDBM50450158'
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Signal transducer and activator of transcription 3 (Homo sapiens (Human))	BDBM50450158 (CHEMBL1933811) Show SMILES Show InChI	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a
University of Macau Curated by ChEMBL					Assay Description Inhibition of NF-kappaB stimulated STAT3 activation in human HeLa cells incubated with NF-kappaB for 16 hrs followed by compound addition measured af...				Bioorg Med Chem 26: 5053-5061 (2018) Article DOI: 10.1016/j.bmc.2018.09.002 BindingDB Entry DOI: 10.7270/Q2ST7SDK
University of Macau Curated by ChEMBL					More data for this Ligand-Target Pair
Signal transducer and activator of transcription 3 (Homo sapiens (Human))	BDBM50450158 (CHEMBL1933811) Show SMILES Show InChI	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	5.80E+3	n/a	n/a	n/a	n/a
University of Macau Curated by ChEMBL					Assay Description Inhibition of IFNgamma-stimulated STAT3 activation in human HeLa cells incubated with IFNgamma for 16 hrs followed by compound addition measured afte...				Bioorg Med Chem 26: 5053-5061 (2018) Article DOI: 10.1016/j.bmc.2018.09.002 BindingDB Entry DOI: 10.7270/Q2ST7SDK
University of Macau Curated by ChEMBL					More data for this Ligand-Target Pair
Signal transducer and activator of transcription 3 (Homo sapiens (Human))	BDBM50450158 (CHEMBL1933811) Show SMILES Show InChI	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a
University of Macau Curated by ChEMBL					Assay Description Inhibition of NF-kappaB stimulated STAT3 activation in human AD293 cells incubated with NF-kappaB for 16 hrs followed by compound addition measured a...				Bioorg Med Chem 26: 5053-5061 (2018) Article DOI: 10.1016/j.bmc.2018.09.002 BindingDB Entry DOI: 10.7270/Q2ST7SDK
University of Macau Curated by ChEMBL					More data for this Ligand-Target Pair
Signal transducer and activator of transcription 3 (Homo sapiens (Human))	BDBM50450158 (CHEMBL1933811) Show SMILES Show InChI	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a
University of Macau Curated by ChEMBL					Assay Description Inhibition of IL-6 stimulated STAT3 activation in human AD293 cells incubated with IL-6 for 16 hrs followed by compound addition measured after 6 hrs...				Bioorg Med Chem 26: 5053-5061 (2018) Article DOI: 10.1016/j.bmc.2018.09.002 BindingDB Entry DOI: 10.7270/Q2ST7SDK
University of Macau Curated by ChEMBL					More data for this Ligand-Target Pair
Signal transducer and activator of transcription 3 (Homo sapiens (Human))	BDBM50450158 (CHEMBL1933811) Show SMILES Show InChI	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	5.05E+3	n/a	n/a	n/a	n/a
University of Macau Curated by ChEMBL					Assay Description Inhibition of IFNgamma-stimulated STAT3 activation in human AD293 cells incubated with IFNgamma for 16 hrs followed by compound addition measured aft...				Bioorg Med Chem 26: 5053-5061 (2018) Article DOI: 10.1016/j.bmc.2018.09.002 BindingDB Entry DOI: 10.7270/Q2ST7SDK
University of Macau Curated by ChEMBL					More data for this Ligand-Target Pair