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Found 1 hit Enz. Inhib. hit(s) with Target = 'Signal transducer and activator of transcription 5B' and Ligand = 'BDBM50033892'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Signal transducer and activator of transcription 5B


(Homo sapiens (Human))
BDBM50033892
PNG
(CHEMBL3358606)
Show SMILES CN(CC(=O)N(Cc1ccc(F)cc1)c1ccc(C(O)=O)c(O)c1)S(=O)(=O)c1c(F)c(F)c(F)c(F)c1F
Show InChI InChI=1S/C23H16F6N2O6S/c1-30(38(36,37)22-20(28)18(26)17(25)19(27)21(22)29)10-16(33)31(9-11-2-4-12(24)5-3-11)13-6-7-14(23(34)35)15(32)8-13/h2-8,32H,9-10H2,1H3,(H,34,35)
PDB

KEGG

UniProtKB/SwissProt

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PC cid
PC sid
UniChem

Similars

Article
PubMed
>6.00E+4n/an/an/an/an/an/an/an/a



University of Toronto Mississauga

Curated by ChEMBL


Assay Description
Inhibition of STAT5B SH2 domain (unknown origin)-5-FAM-GpYLVLDKW interaction compound treated for 15 mins by fluorescent polarization assay


ACS Med Chem Lett 5: 1202-1206 (2014)


Article DOI: 10.1021/ml500165r
BindingDB Entry DOI: 10.7270/Q25X2BJJ
More data for this
Ligand-Target Pair