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Compile Data Set for Download or QSAR

Found 2 hits Enz. Inhib. hit(s) with Target = 'Signal transducer and activator of transcription 6' and Ligand = 'BDBM50243934'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Signal transducer and activator of transcription 6


(Homo sapiens (Human))
BDBM50243934
PNG
(2-[(4-Morpholin-4-ylphenyl)amino]-4-[(2,3,6-triflu...)
Show SMILES NC(=O)c1cnc(Nc2ccc(cc2)N2CCOCC2)nc1NCc1c(F)cc(F)cc1F
Show InChI InChI=1S/C22H21F3N6O2/c23-13-9-18(24)16(19(25)10-13)11-27-21-17(20(26)32)12-28-22(30-21)29-14-1-3-15(4-2-14)31-5-7-33-8-6-31/h1-4,9-10,12H,5-8,11H2,(H2,26,32)(H2,27,28,29,30)
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Article
PubMed
n/an/a 0.700n/an/an/an/an/an/a



Astellas Pharma Inc.

Curated by ChEMBL


Assay Description
Inhibition of STAT6 activation (unknown origin) in FW4 reporter cells


Bioorg Med Chem 16: 6509-21 (2008)


Article DOI: 10.1016/j.bmc.2008.05.031
BindingDB Entry DOI: 10.7270/Q2VD6Z7H
More data for this
Ligand-Target Pair
Signal transducer and activator of transcription 6


(Homo sapiens (Human))
BDBM50243934
PNG
(2-[(4-Morpholin-4-ylphenyl)amino]-4-[(2,3,6-triflu...)
Show SMILES NC(=O)c1cnc(Nc2ccc(cc2)N2CCOCC2)nc1NCc1c(F)cc(F)cc1F
Show InChI InChI=1S/C22H21F3N6O2/c23-13-9-18(24)16(19(25)10-13)11-27-21-17(20(26)32)12-28-22(30-21)29-14-1-3-15(4-2-14)31-5-7-33-8-6-31/h1-4,9-10,12H,5-8,11H2,(H2,26,32)(H2,27,28,29,30)
PDB

NCI pathway
Reactome pathway
KEGG

UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 88n/an/an/an/an/an/a



Astellas Pharma Inc.

Curated by ChEMBL


Assay Description
Inhibition of STAT6 activation (unknown origin) in FW4 reporter cells


Bioorg Med Chem 16: 6509-21 (2008)


Article DOI: 10.1016/j.bmc.2008.05.031
BindingDB Entry DOI: 10.7270/Q2VD6Z7H
More data for this
Ligand-Target Pair