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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Signal transducer and activator of transcription 6' and Ligand = 'BDBM50304427'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Signal transducer and activator of transcription 6


(Homo sapiens (Human))
BDBM50304427
PNG
(7-(4-Fluorobenzyl)-N-(4-morpholin-4-ylphenyl)-7Hpy...)
Show SMILES Fc1ccc(Cn2ccc3cnc(Nc4ccc(cc4)N4CCOCC4)nc23)cc1
Show InChI InChI=1S/C23H22FN5O/c24-19-3-1-17(2-4-19)16-29-10-9-18-15-25-23(27-22(18)29)26-20-5-7-21(8-6-20)28-11-13-30-14-12-28/h1-10,15H,11-14,16H2,(H,25,26,27)
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PC cid
PC sid
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Similars

Article
PubMed
n/an/a 4.10E+3n/an/an/an/an/an/a



Astellas Pharma Inc.

Curated by ChEMBL


Assay Description
Inhibition of STAT6 in IL4-stimulated human FW4 reporter cells by luciferase assay


Bioorg Med Chem 17: 6926-36 (2009)


Article DOI: 10.1016/j.bmc.2009.08.021
BindingDB Entry DOI: 10.7270/Q2RV0NS7
More data for this
Ligand-Target Pair