Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Sodium/calcium exchanger 1' and Ligand = 'BDBM140887'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Sodium/calcium exchanger 1 (Homo sapiens (Human))	BDBM140887 (US8912224, 325) Show SMILES Cc1ccccc1[C@H]1CCc2cc(Oc3ncc(s3)C(=O)NCCO)ccc2O1 Show InChI InChI=1S/C22H22N2O4S/c1-14-4-2-3-5-17(14)19-8-6-15-12-16(7-9-18(15)28-19)27-22-24-13-20(29-22)21(26)23-10-11-25/h2-5,7,9,12-13,19,25H,6,8,10-11H2,1H3,(H,23,26)/t19-/m1/s1	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	KEGG PC cid PC sid UniChem Similars	US Patent	n/a	n/a	200	n/a	n/a	n/a	n/a	n/a	n/a
Sanofi US Patent					Assay Description The assay is based on the monitoring of intracellular Ca2+concentrations using the calcium-sensitive dye Fluo-4. CHO cells expressing NCX1 were loade...				US Patent US8912224 (2014) BindingDB Entry DOI: 10.7270/Q22F7M52
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