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Found 1 hit Enz. Inhib. hit(s) with Target = 'Sodium/glucose cotransporter 1' and Ligand = 'BDBM50235127'   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Sodium/glucose cotransporter 1


(Homo sapiens (Human))		BDBM50235127
PNG
(CHEMBL1645378)
Show SMILES OC[C@H]1O[C@H]([C@H](O)[C@@H](O)[C@@H]1O)c1c(O)cc(O)c(C(=O)CCc2ccccc2)c1O |r|
Show InChI InChI=1S/C21H24O9/c22-9-14-17(26)19(28)20(29)21(30-14)16-13(25)8-12(24)15(18(16)27)11(23)7-6-10-4-2-1-3-5-10/h1-5,8,14,17,19-22,24-29H,6-7,9H2/t14-,17-,19+,20-,21+/m1/s1
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Similars
Article
PubMed
n/an/a 9.90E+3n/an/an/an/an/an/a



Universidade de Lisboa

Curated by ChEMBL


Assay Description
Inhibition of human SGLT1 expressed in HEK293 cells assessed as reduction in 2-deoxyglucose uptake pretreated for 10 mins followed by 2-deoxyglucose ...

J Med Chem 60: 568-579 (2017)


Article DOI: 10.1021/acs.jmedchem.6b01134
BindingDB Entry DOI: 10.7270/Q2KK9F2F
More data for this
Ligand-Target Pair