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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Sodium/glucose cotransporter 1' and Ligand = 'BDBM50235128'   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Sodium/glucose cotransporter 1


(Homo sapiens (Human))		BDBM50235128
PNG
(CHEMBL4082151)
Show SMILES OC[C@H]1O[C@H]([C@H](O)[C@@H](O)[C@@H]1O)c1c(O)cc(O)c(C(=O)CCc2ccc(F)cc2)c1O |r|
Show InChI InChI=1S/C21H23FO9/c22-10-4-1-9(2-5-10)3-6-11(24)15-12(25)7-13(26)16(18(15)28)21-20(30)19(29)17(27)14(8-23)31-21/h1-2,4-5,7,14,17,19-21,23,25-30H,3,6,8H2/t14-,17-,19+,20-,21+/m1/s1
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Similars
Article
PubMed
n/an/a 9.70E+3n/an/an/an/an/an/a



Universidade de Lisboa

Curated by ChEMBL


Assay Description
Inhibition of human SGLT1 expressed in HEK293 cells assessed as reduction in 2-deoxyglucose uptake pretreated for 10 mins followed by 2-deoxyglucose ...

J Med Chem 60: 568-579 (2017)


Article DOI: 10.1021/acs.jmedchem.6b01134
BindingDB Entry DOI: 10.7270/Q2KK9F2F
More data for this
Ligand-Target Pair