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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Sodium/glucose cotransporter 1' and Ligand = 'BDBM50335144'   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Sodium/glucose cotransporter 1


(Homo sapiens (Human))		BDBM50335144
PNG
(4-Chloro-3-[4-(N,N-dimethylamino)benzyl]-1-(beta-D...)
Show SMILES CN(C)c1ccc(Cc2cn([C@@H]3OC[C@@H](O)[C@H](O)[C@H]3O)c3cccc(Cl)c23)cc1 |r|
Show InChI InChI=1S/C22H25ClN2O4/c1-24(2)15-8-6-13(7-9-15)10-14-11-25(17-5-3-4-16(23)19(14)17)22-21(28)20(27)18(26)12-29-22/h3-9,11,18,20-22,26-28H,10,12H2,1-2H3/t18-,20+,21-,22-/m1/s1
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Similars
Article
PubMed
n/an/an/an/a 629n/an/an/an/a



Taiwan National Health Research Institutes

Curated by ChEMBL


Assay Description
Inhibition of human SGLT1 expressed in CHO cells assessed as sodium-dependent [14C]-alpha-methyl-D-glucopyranoside uptake after 2 hrs by liquid scint...

J Med Chem 54: 166-78 (2011)


Article DOI: 10.1021/jm101072y
BindingDB Entry DOI: 10.7270/Q2445NG8
More data for this
Ligand-Target Pair