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Found 1 hit Enz. Inhib. hit(s) with Target = 'Sodium/glucose cotransporter 1' and Ligand = 'BDBM50449245'   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Sodium/glucose cotransporter 1


(Homo sapiens (Human))		BDBM50449245
PNG
(CHEMBL3125149)
Show SMILES CCOC(=O)c1nnn(c1[C@H](O)[C@@H](O)[C@H](C)O)-c1cc2oc3ccccc3c2cc1OC |r|
Show InChI InChI=1S/C22H23N3O7/c1-4-31-22(29)18-19(21(28)20(27)11(2)26)25(24-23-18)14-10-16-13(9-17(14)30-3)12-7-5-6-8-15(12)32-16/h5-11,20-21,26-28H,4H2,1-3H3/t11-,20-,21-/m0/s1
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Article
PubMed
n/an/a 626n/an/an/an/an/an/a



CSIR-Indian Institute of Chemical Technology

Curated by ChEMBL


Assay Description
Inhibition of SGLT1 (unknown origin) expressed in HEK293 cells using 2-NBDG as substrate incubated for 30 mins prior to substrate addition measured a...

Bioorg Med Chem Lett 24: 1528-31 (2014)


Article DOI: 10.1016/j.bmcl.2014.01.077
BindingDB Entry DOI: 10.7270/Q2PG1T6N
More data for this
Ligand-Target Pair