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Found 1 hit Enz. Inhib. hit(s) with Target = 'Sodium/glucose cotransporter 2' and Ligand = 'BDBM50208611'   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Sodium/glucose cotransporter 2


(Homo sapiens (Human))		BDBM50208611
PNG
((2S)-2-(2,4-dihydroxyphenyl)-5,7-dihydroxy-8-[(2R)...)
Show SMILES [#6]\[#6](-[#6])=[#6]\[#6]-[#6@H](-[#6]-c1c(-[#8])cc(-[#8])c2-[#6](=O)-[#6]-[#6@H](-[#8]-c12)-c1ccc(-[#8])cc1-[#8])-[#6](-[#6])=[#6] |r|
Show InChI InChI=1S/C25H28O6/c1-13(2)5-6-15(14(3)4)9-18-20(28)11-21(29)24-22(30)12-23(31-25(18)24)17-8-7-16(26)10-19(17)27/h5,7-8,10-11,15,23,26-29H,3,6,9,12H2,1-2,4H3/t15-,23+/m1/s1
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Similars
Article
PubMed
n/an/a 4.10E+3n/an/an/an/an/an/a



Nippon Suisan Kaisha, Ltd

Curated by ChEMBL


Assay Description
Inhibition of human SGLT2 expressed in COS1 cells assessed as [14C]methyl-alpha-D-glucopyranoside uptake

Bioorg Med Chem 15: 3445-9 (2007)


Article DOI: 10.1016/j.bmc.2007.03.011
BindingDB Entry DOI: 10.7270/Q25X28N2
More data for this
Ligand-Target Pair