Compile Data Set for Download or QSAR

Found 2 hits Enz. Inhib. hit(s) with Target = 'Sodium/glucose cotransporter 2' and Ligand = 'BDBM50319050'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Sodium/glucose cotransporter 2 (Homo sapiens (Human))	BDBM50319050 ((2S,3R,4R,5S,6R)-2-(4-chloro-3-((6-(phenylthio)pyr...) Show SMILES OC[C@H]1O[C@H]([C@H](O)[C@@H](O)[C@@H]1O)c1ccc(Cl)c(Cc2ccc(Sc3ccccc3)nn2)c1 |r| Show InChI InChI=1S/C23H23ClN2O5S/c24-17-8-6-13(23-22(30)21(29)20(28)18(12-27)31-23)10-14(17)11-15-7-9-19(26-25-15)32-16-4-2-1-3-5-16/h1-10,18,20-23,27-30H,11-12H2/t18-,20-,21+,22-,23+/m1/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.87E+3	n/a	n/a	n/a	n/a	n/a	n/a
Green Cross Corporation Curated by ChEMBL					Assay Description Inhibition of human SGLT2 expressed in CHO cells assessed as [14C]-alpha-methyl-D-glucopyranoside uptake after 2 hrs by liquid scintillation counting				Bioorg Med Chem Lett 20: 3420-5 (2010) Article DOI: 10.1016/j.bmcl.2010.04.006 BindingDB Entry DOI: 10.7270/Q24J0F8B
					More data for this Ligand-Target Pair
Sodium/glucose cotransporter 2 (Homo sapiens (Human))	BDBM50319050 ((2S,3R,4R,5S,6R)-2-(4-chloro-3-((6-(phenylthio)pyr...) Show SMILES OC[C@H]1O[C@H]([C@H](O)[C@@H](O)[C@@H]1O)c1ccc(Cl)c(Cc2ccc(Sc3ccccc3)nn2)c1 |r| Show InChI InChI=1S/C23H23ClN2O5S/c24-17-8-6-13(23-22(30)21(29)20(28)18(12-27)31-23)10-14(17)11-15-7-9-19(26-25-15)32-16-4-2-1-3-5-16/h1-10,18,20-23,27-30H,11-12H2/t18-,20-,21+,22-,23+/m1/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	US Patent	n/a	n/a	1.87E+3	n/a	n/a	n/a	n/a	n/a	n/a
Green Cross Corporation US Patent					Assay Description Inhibition assay using hSGLT2.				US Patent US8541380 (2013) BindingDB Entry DOI: 10.7270/Q2T43RQ3
					More data for this Ligand-Target Pair