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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Sodium/glucose cotransporter 2' and Ligand = 'BDBM50335149'   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Sodium/glucose cotransporter 2


(Homo sapiens (Human))		BDBM50335149
PNG
(4-Chloro-3-{4-[2-(2-ethoxyethoxy)ethoxy]benzyl}-1-...)
Show SMILES CCOCCOCCOc1ccc(Cc2cn([C@@H]3OC[C@@H](O)[C@H](O)[C@H]3O)c3cccc(Cl)c23)cc1 |r|
Show InChI InChI=1S/C26H32ClNO7/c1-2-32-10-11-33-12-13-34-19-8-6-17(7-9-19)14-18-15-28(21-5-3-4-20(27)23(18)21)26-25(31)24(30)22(29)16-35-26/h3-9,15,22,24-26,29-31H,2,10-14,16H2,1H3/t22-,24+,25-,26-/m1/s1
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Similars
Article
PubMed
n/an/an/an/a 577n/an/an/an/a



Taiwan National Health Research Institutes

Curated by ChEMBL


Assay Description
Inhibition of human SGLT2 expressed in CHO cells assessed as sodium-dependent [14C]-alpha-methyl-D-glucopyranoside uptake after 2 hrs by liquid scint...

J Med Chem 54: 166-78 (2011)


Article DOI: 10.1021/jm101072y
BindingDB Entry DOI: 10.7270/Q2445NG8
More data for this
Ligand-Target Pair