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Found 1 hit Enz. Inhib. hit(s) with Target = 'Sodium/glucose cotransporter 2' and Ligand = 'BDBM50340007'   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Sodium/glucose cotransporter 2


(Homo sapiens (Human))		BDBM50340007
PNG
(4-((4-butyl-5-(4-chlorophenethyl)-4H-1,2,4-triazol...)
Show SMILES CCCCn1c(CCc2ccc(Cl)cc2)nnc1CN1C(=O)COc2ccc(Cl)cc12
Show InChI InChI=1S/C23H24Cl2N4O2/c1-2-3-12-28-21(11-6-16-4-7-17(24)8-5-16)26-27-22(28)14-29-19-13-18(25)9-10-20(19)31-15-23(29)30/h4-5,7-10,13H,2-3,6,11-12,14-15H2,1H3
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PC sid
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Similars
Article
PubMed
n/an/a 30n/an/an/an/an/an/a



Amgen Inc.

Curated by ChEMBL


Assay Description
Inhibition of human SGLT2 expressed in CHO cells assessed as inhibition of [14C]-alpha-methyl-D-glucopyranoside transport after 60 mins by scintillat...

Bioorg Med Chem Lett 21: 2472-5 (2011)


Article DOI: 10.1016/j.bmcl.2011.02.056
BindingDB Entry DOI: 10.7270/Q25Q4WD2
More data for this
Ligand-Target Pair