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Found 1 hit Enz. Inhib. hit(s) with Target = 'Sodium/glucose cotransporter 2' and Ligand = 'BDBM50340008'   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Sodium/glucose cotransporter 2


(Homo sapiens (Human))		BDBM50340008
PNG
(6-chloro-4-((5-(4-chlorophenethyl)-4-(cyclopropylm...)
Show SMILES Clc1ccc(CCc2nnc(CN3C(=O)COc4ccc(Cl)cc34)n2CC2CC2)cc1
Show InChI InChI=1S/C23H22Cl2N4O2/c24-17-6-3-15(4-7-17)5-10-21-26-27-22(29(21)12-16-1-2-16)13-28-19-11-18(25)8-9-20(19)31-14-23(28)30/h3-4,6-9,11,16H,1-2,5,10,12-14H2
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Article
PubMed
n/an/a 30n/an/an/an/an/an/a



Amgen Inc.

Curated by ChEMBL


Assay Description
Inhibition of human SGLT2 expressed in CHO cells assessed as inhibition of [14C]-alpha-methyl-D-glucopyranoside transport after 60 mins by scintillat...

Bioorg Med Chem Lett 21: 2472-5 (2011)


Article DOI: 10.1016/j.bmcl.2011.02.056
BindingDB Entry DOI: 10.7270/Q25Q4WD2
More data for this
Ligand-Target Pair