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Found 1 hit Enz. Inhib. hit(s) with Target = 'Sodium/glucose cotransporter 2' and Ligand = 'BDBM50441086'   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Sodium/glucose cotransporter 2


(Homo sapiens (Human))		BDBM50441086
PNG
(CHEMBL2430317)
Show SMILES CCc1ccc(Cc2ccc(=O)n(c2)[C@@H]2O[C@H](CO)[C@@H](O)[C@H](O)[C@H]2O)cc1 |r|
Show InChI InChI=1S/C20H25NO6/c1-2-12-3-5-13(6-4-12)9-14-7-8-16(23)21(10-14)20-19(26)18(25)17(24)15(11-22)27-20/h3-8,10,15,17-20,22,24-26H,2,9,11H2,1H3/t15-,17-,18+,19-,20-/m1/s1
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n/an/a 163n/an/an/an/an/an/a



Mitsubishi Tanabe Pharma Corporation

Curated by ChEMBL


Assay Description
Inhibition of human SGLT2 expressed in CHOK cells assessed as [14-C]AMG uptake preincubated for 10 mins followed by [14-C]AMG addition measured after...

Bioorg Med Chem Lett 23: 5641-5 (2013)


Article DOI: 10.1016/j.bmcl.2013.08.042
BindingDB Entry DOI: 10.7270/Q2TX3GSM
More data for this
Ligand-Target Pair