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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Sodium/glucose cotransporter 2' and Ligand = 'BDBM50446183'   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Sodium/glucose cotransporter 2


(Homo sapiens (Human))		BDBM50446183
PNG
(CHEMBL3109013)
Show SMILES OC[C@H]1O[C@H]([C@H](O)[C@@H](O)[C@@H]1O)n1cc(Cc2ccc(cc2)C2CCCC2)c2ccccc12 |r|
Show InChI InChI=1S/C26H31NO5/c28-15-22-23(29)24(30)25(31)26(32-22)27-14-19(20-7-3-4-8-21(20)27)13-16-9-11-18(12-10-16)17-5-1-2-6-17/h3-4,7-12,14,17,22-26,28-31H,1-2,5-6,13,15H2/t22-,23-,24+,25-,26-/m1/s1
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n/an/a 93n/an/an/an/an/an/a



Mitsubishi Tanabe Pharma Corporation

Curated by ChEMBL


Assay Description
Inhibition of human SGLT2-mediated [14C]-AMG uptake expressed in CHOK cells preincubated for 10 mins followed by [14C]-AMG addition measured after 12...

ACS Med Chem Lett 5: 51-5 (2014)


Article DOI: 10.1021/ml400339b
BindingDB Entry DOI: 10.7270/Q24J0GM7
More data for this
Ligand-Target Pair