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Found 1 hit Enz. Inhib. hit(s) with Target = 'Sodium/hydrogen exchanger 1' and Ligand = 'BDBM50297562'   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Sodium/hydrogen exchanger 1


(Rattus norvegicus)		BDBM50297562
PNG
(CHEMBL563178 | N''-[2-(1,3-benzothiazol-2-ylthio)-...)
Show SMILES [#6]-[#8]-c1cc2-[#6]-[#6](-[#16]-c3nc4ccccc4s3)-[#6](=[#7]\[#7]=[#6](\[#7])-[#7])-c2cc1-[#8]-[#6] |w:18.20|
Show InChI InChI=1S/C19H19N5O2S2/c1-25-13-7-10-8-16(28-19-22-12-5-3-4-6-15(12)27-19)17(23-24-18(20)21)11(10)9-14(13)26-2/h3-7,9,16H,8H2,1-2H3,(H4,20,21,24)
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PubMed
n/an/a 2.44n/an/an/an/an/an/a



China Pharmaceutical University

Curated by ChEMBL


Assay Description
Inhibition of NHE1 in Sprague-Dawley rat platelet-rich plasma by optical swelling assay

Eur J Med Chem 44: 3771-6 (2009)


Article DOI: 10.1016/j.ejmech.2009.04.036
BindingDB Entry DOI: 10.7270/Q2474BS7
More data for this
Ligand-Target Pair