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Found 1 hit Enz. Inhib. hit(s) with Target = 'Sodium/hydrogen exchanger 1' and Ligand = 'BDBM50297578'   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Sodium/hydrogen exchanger 1


(Rattus norvegicus)		BDBM50297578
PNG
(2-{[(1E)-2-(1,3-benzothiazol-2-ylsulfanyl)-4,5,6-t...)
Show SMILES [#6]-[#8]-c1cc2-[#6](=[#7]\[#7]=[#6](\[#7])-[#7])-[#6](-[#6]-c2c(-[#8]-[#6])c1-[#8]-[#6])-[#16]-c1nc2ccccc2s1 |w:6.6|
Show InChI InChI=1S/C20H21N5O3S2/c1-26-13-8-10-11(17(27-2)18(13)28-3)9-15(16(10)24-25-19(21)22)30-20-23-12-6-4-5-7-14(12)29-20/h4-8,15H,9H2,1-3H3,(H4,21,22,25)
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Article
PubMed
n/an/a 1.98n/an/an/an/an/an/a



China Pharmaceutical University

Curated by ChEMBL


Assay Description
Inhibition of NHE1 in Sprague-Dawley rat platelet-rich plasma by optical swelling assay

Eur J Med Chem 44: 3771-6 (2009)


Article DOI: 10.1016/j.ejmech.2009.04.036
BindingDB Entry DOI: 10.7270/Q2474BS7
More data for this
Ligand-Target Pair