BindingDB logo
myBDB logout
Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Sodium/hydrogen exchanger 3' and Ligand = 'BDBM50471145'   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Sodium/hydrogen exchanger 3


(Oryctolagus cuniculus)		BDBM50471145
PNG
(CHEMBL64132)
Show SMILES [#6]-c1cc(-[#7])c(cc1-[#6](=O)\[#7]=[#6](\[#7])-[#7])S([#6])(=O)=O
Show InChI InChI=1S/C10H14N4O3S/c1-5-3-7(11)8(18(2,16)17)4-6(5)9(15)14-10(12)13/h3-4H,11H2,1-2H3,(H4,12,13,14,15)
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
Article
PubMed
n/an/a 16n/an/an/an/an/an/a



Merck KGaA

Curated by ChEMBL


Assay Description
Inhibition of 5-N-(ethyl isopropyl)-amiloride[EIPA]-sensitive Na+ uptake into acidified rabbit erythrocytes.

J Med Chem 40: 2017-34 (1997)


Article DOI: 10.1021/jm960768n
BindingDB Entry DOI: 10.7270/Q28055BJ
More data for this
Ligand-Target Pair