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Found 1 hit Enz. Inhib. hit(s) with Target = 'Sodium/hydrogen exchanger 3' and Ligand = 'BDBM50471251'   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Sodium/hydrogen exchanger 3


(Oryctolagus cuniculus)		BDBM50471251
PNG
(CHEMBL60249)
Show SMILES [#6]-c1cc(-[#8]-c2cccnc2)c(cc1-[#6](=O)\[#7]=[#6](\[#7])-[#7])S([#6])(=O)=O
Show InChI InChI=1S/C15H16N4O4S/c1-9-6-12(23-10-4-3-5-18-8-10)13(24(2,21)22)7-11(9)14(20)19-15(16)17/h3-8H,1-2H3,(H4,16,17,19,20)
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
Article
PubMed
n/an/a 8.80n/an/an/an/an/an/a



Merck KGaA

Curated by ChEMBL


Assay Description
Inhibition of 5-N-(ethyl isopropyl)-amiloride[EIPA]-sensitive Na+ uptake into acidified rabbit erythrocytes.

J Med Chem 40: 2017-34 (1997)


Article DOI: 10.1021/jm960768n
BindingDB Entry DOI: 10.7270/Q28055BJ
More data for this
Ligand-Target Pair