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Found 1 hit Enz. Inhib. hit(s) with Target = 'Sodium/nucleoside cotransporter 2' and Ligand = 'BDBM50085465'   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Sodium/nucleoside cotransporter 2


(Homo sapiens (Human))		BDBM50085465
PNG
(CHEMBL3427696)
Show SMILES CCOC(=O)OC[C@H]1O[C@H]([C@H](O)[C@@H]1O)n1cnc2c(N)ncnc12 |r|
Show InChI InChI=1S/C13H17N5O6/c1-2-22-13(21)23-3-6-8(19)9(20)12(24-6)18-5-17-7-10(14)15-4-16-11(7)18/h4-6,8-9,12,19-20H,2-3H2,1H3,(H2,14,15,16)/t6-,8-,9-,12-/m1/s1
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Similars
Article
PubMed
n/an/a>1.00E+5n/an/an/an/an/an/a



Kissei Pharmaceutical Co., Ltd.

Curated by ChEMBL


Assay Description
Inhibition of human CNT2 expressed in COS7 cells assessed as reduction in sodium-dependent [14C]-inosine uptake in presence of Na+ by liquid scintill...

ACS Med Chem Lett 6: 244-8 (2015)


Article DOI: 10.1021/ml500343r
BindingDB Entry DOI: 10.7270/Q2BK1F27
More data for this
Ligand-Target Pair