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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Sodium/nucleoside cotransporter 2' and Ligand = 'BDBM50085547'   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Sodium/nucleoside cotransporter 2


(Homo sapiens (Human))		BDBM50085547
PNG
(CHEMBL3427670)
Show SMILES Nc1ncnc2n([C@@H]3O[C@H](CO)[C@@H](O)[C@H]3O)c(NCCCc3ccccc3)nc12 |r|
Show InChI InChI=1S/C19H24N6O4/c20-16-13-17(23-10-22-16)25(18-15(28)14(27)12(9-26)29-18)19(24-13)21-8-4-7-11-5-2-1-3-6-11/h1-3,5-6,10,12,14-15,18,26-28H,4,7-9H2,(H,21,24)(H2,20,22,23)/t12-,14-,15-,18-/m1/s1
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Similars
Article
PubMed
n/an/a 5.36E+5n/an/an/an/an/an/a



Kissei Pharmaceutical Co., Ltd.

Curated by ChEMBL


Assay Description
Inhibition of human CNT2 expressed in COS7 cells assessed as reduction in sodium-dependent [14C]-inosine uptake in presence of Na+ by liquid scintill...

ACS Med Chem Lett 6: 244-8 (2015)


Article DOI: 10.1021/ml500343r
BindingDB Entry DOI: 10.7270/Q2BK1F27
More data for this
Ligand-Target Pair