Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Sodium channel protein type 1/2/3 subunit alpha (Rattus norvegicus) | BDBM50031299 (6-(2,3-Dichloro-phenyl)-[1,2,4]triazine-3,5-diamin...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | Purchase CHEMBL DrugBank MCE PC cid PC sid PDB UniChem Patents | PubMed | n/a | n/a | 3.10E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Institut Henri Beaufour Curated by ChEMBL | Assay Description Concentration required to inhibit [3H]BTX binding to Sodium channel of rat brain | Bioorg Med Chem Lett 14: 3521-3 (2004) BindingDB Entry DOI: 10.7270/Q2474D2N | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Sodium channel protein type 1/2/3 subunit alpha (Rattus norvegicus) | BDBM50031299 (6-(2,3-Dichloro-phenyl)-[1,2,4]triazine-3,5-diamin...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | Purchase CHEMBL DrugBank MCE PC cid PC sid PDB UniChem Patents | PubMed | n/a | n/a | >1.00E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
Pharmacia& Upjohn Curated by ChEMBL | Assay Description Inhibition of [3H]saxitoxin binding to rat brain sodium channel | Bioorg Med Chem Lett 9: 2521-4 (1999) BindingDB Entry DOI: 10.7270/Q29887HT | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Sodium channel protein type 1/2/3 subunit alpha (Rattus norvegicus) | BDBM50031299 (6-(2,3-Dichloro-phenyl)-[1,2,4]triazine-3,5-diamin...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | Purchase CHEMBL DrugBank MCE PC cid PC sid PDB UniChem Patents | Article PubMed | n/a | n/a | 1.14E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
Howard University Curated by ChEMBL | Assay Description Inhibition of [3H]BTX-B binding to neurotoxin site 2 of sodium channel of rat cerebral cortex synaptoneurosomes | J Med Chem 38: 4033-43 (1995) Article DOI: 10.1021/jm00020a019 BindingDB Entry DOI: 10.7270/Q2DV1NM8 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Sodium channel protein type 1/2/3 subunit alpha (Rattus norvegicus) | BDBM50031299 (6-(2,3-Dichloro-phenyl)-[1,2,4]triazine-3,5-diamin...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | Purchase CHEMBL DrugBank MCE PC cid PC sid PDB UniChem Patents | PubMed | n/a | n/a | 1.86E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
Pharmacia& Upjohn Curated by ChEMBL | Assay Description Inhibition of [3H]batrachotoxin binding to rat brain sodium channel | Bioorg Med Chem Lett 9: 2521-4 (1999) BindingDB Entry DOI: 10.7270/Q29887HT | |||||||||||
More data for this Ligand-Target Pair |