Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Sodium channel protein type 10 subunit alpha' and Ligand = 'BDBM160991'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Sodium channel protein type 10 subunit alpha (Rattus norvegicus (Rat))	BDBM160991 (US9108903, 56) Show SMILES OC(=O)c1ccc(NC(=O)c2ccc(cc2Oc2ccc(F)cc2)C(F)(F)F)cn1 Show InChI InChI=1S/C20H12F4N2O4/c21-12-2-5-14(6-3-12)30-17-9-11(20(22,23)24)1-7-15(17)18(27)26-13-4-8-16(19(28)29)25-10-13/h1-10H,(H,26,27)(H,28,29)	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	250	n/a	n/a	n/a	n/a	n/a	n/a
VERTEX PHARMACEUTICALS INCORPORATED US Patent					Assay Description Patch clamp electrophysiology was used to assess the efficacy and selectivity of sodium channel blockers in dorsal root ganglion neurons. Rat neurons...				US Patent US9108903 (2015) BindingDB Entry DOI: 10.7270/Q23J3BP9
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