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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Sodium channel protein type 10 subunit alpha' and Ligand = 'BDBM50426578'   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Sodium channel protein type 10 subunit alpha


(Homo sapiens (Human))		BDBM50426578
PNG
(CHEMBL2324352)
Show SMILES CC(C)(C)C(=O)ON[C@H](Cc1ccccc1)C(=O)N[C@@H]1CCc2ccccc2N(CC(F)(F)F)C1=O |r|
Show InChI InChI=1S/C26H30F3N3O4/c1-25(2,3)24(35)36-31-20(15-17-9-5-4-6-10-17)22(33)30-19-14-13-18-11-7-8-12-21(18)32(23(19)34)16-26(27,28)29/h4-12,19-20,31H,13-16H2,1-3H3,(H,30,33)/t19-,20-/m1/s1
PDB

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PC sid
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Article
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n/an/a 680n/an/an/an/an/an/a



Pfizer Inc.

Curated by ChEMBL


Assay Description
Inhibition of human voltage-gated Na channel 1.8 expressed in HEK293 cells

J Med Chem 56: 593-624 (2013)


Article DOI: 10.1021/jm3011433
BindingDB Entry DOI: 10.7270/Q23B61GZ
More data for this
Ligand-Target Pair