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Found 1 hit Enz. Inhib. hit(s) with Target = 'Sodium channel protein type 10 subunit alpha' and Ligand = 'BDBM50507845'   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Sodium channel protein type 10 subunit alpha


(Homo sapiens (Human))		BDBM50507845
PNG
(CHEMBL4455868)
Show SMILES CO[C@H](C)[C@H](N)c1nc2cc(ccc2[nH]1)-c1ccc(cc1F)C#N |r|
Show InChI InChI=1S/C18H17FN4O/c1-10(24-2)17(21)18-22-15-6-4-12(8-16(15)23-18)13-5-3-11(9-20)7-14(13)19/h3-8,10,17H,21H2,1-2H3,(H,22,23)/t10-,17+/m1/s1
PDB

UniProtKB/SwissProt

antibodypedia
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PC cid
PC sid
UniChem
Article
PubMed
n/an/a 18n/an/an/an/an/an/a



Pfizer Inc.

Curated by ChEMBL


Assay Description
Inhibition of human Nav1.8 expressed in HEK cells by patch-clamp electrophysiology method

Bioorg Med Chem 27: 230-239 (2019)


Article DOI: 10.1016/j.bmc.2018.12.002
BindingDB Entry DOI: 10.7270/Q2ZK5KZN
More data for this
Ligand-Target Pair