Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Sodium channel protein type 5 subunit alpha/subunit beta-1/subunit beta-2 (Homo sapiens (Human)) | BDBM258128 (US9493448, 30 | US9845313, Example 30) | PDB UniProtKB/SwissProt antibodypedia antibodypedia antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 8.40E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Daiichi Sankyo Co., Ltd. Curated by ChEMBL | Assay Description Inhibition of human NaV1.5/beta1/beta2 expressed in HEK293A cells by Ionworks high-throughput electrophysiology method | J Med Chem 63: 10204-10220 (2020) Article DOI: 10.1021/acs.jmedchem.0c00259 BindingDB Entry DOI: 10.7270/Q2Q52T67 | |||||||||||
More data for this Ligand-Target Pair |