Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Sodium channel protein type 5 subunit alpha' and Ligand = 'BDBM50103578'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Sodium channel protein type 5 subunit alpha (Homo sapiens (Human))	BDBM50103578 (CHEMBL3337589) Show SMILES COc1ccc-2c(N[C@@]3(CCN(C[C@@H]3C)C(=O)c3ccc(OC)c(c3)N(C)C)c3cccn-23)c1 |r| Show InChI InChI=1S/C27H32N4O3/c1-18-17-30(26(32)19-8-11-24(34-5)23(15-19)29(2)3)14-12-27(18)25-7-6-13-31(25)22-10-9-20(33-4)16-21(22)28-27/h6-11,13,15-16,18,28H,12,14,17H2,1-5H3/t18-,27+/m0/s1	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	519	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratory Curated by ChEMBL					Assay Description Inhibition of human Nav1.5 expressed in HEK293 cells after 60 mins by FLIPR assay				Bioorg Med Chem Lett 24: 4958-62 (2014) Article DOI: 10.1016/j.bmcl.2014.09.038 BindingDB Entry DOI: 10.7270/Q21Z465T
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