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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Sodium channel protein type 5 subunit alpha' and Ligand = 'BDBM50169429'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Sodium channel protein type 5 subunit alpha


(Homo sapiens (Human))
BDBM50169429
PNG
(CHEMBL3805199 | US9481677, 32)
Show SMILES Fc1cc(c(F)cc1Oc1ccc(Cl)cc1-c1cnc2CNCCn12)S(=O)(=O)Nc1ncns1
Show InChI InChI=1S/C20H15ClF2N6O3S2/c21-11-1-2-16(12(5-11)15-8-25-19-9-24-3-4-29(15)19)32-17-6-14(23)18(7-13(17)22)34(30,31)28-20-26-10-27-33-20/h1-2,5-8,10,24H,3-4,9H2,(H,26,27,28)
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
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CHEMBL
PC cid
PC sid
UniChem

Patents

PubMed
n/an/a>1.00E+4n/an/an/an/an/an/a



Xenon Pharmaceuticals, Inc.

Curated by ChEMBL


Assay Description
Inhibition of full length human Nav1.5 channel expressed in HEK cells co-expressing human sodium channel subunit beta1 at holding potential -60 mV by...


ACS Med Chem Lett 7: 277-82 (2016)


BindingDB Entry DOI: 10.7270/Q2J1052W
More data for this
Ligand-Target Pair