Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Sodium channel protein type 7 subunit alpha (Homo sapiens (Human)) | BDBM145375 (US8952169, 154) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 2.20 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Displacement of [3H]GX-545 Nav1.7 (unknown origin) expressed in HEK cells by liquid scintillation counting based radioligand competition assay | Citation and Details Article DOI: 10.1021/acs.jmedchem.1c00049 BindingDB Entry DOI: 10.7270/Q2WW7NKS | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Sodium channel protein type 7 subunit alpha (Homo sapiens (Human)) | BDBM145375 (US8952169, 154) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 160 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Inhibition of human Nav1.7 expressed in HEK293 cells incubated for 1 hr in presence of veratridine by sodium influx assay | Citation and Details Article DOI: 10.1021/acs.jmedchem.1c00049 BindingDB Entry DOI: 10.7270/Q2WW7NKS | |||||||||||
More data for this Ligand-Target Pair |